2019 Course Outcomes

The course assessment method will be by the use of quizzes at the end of each session. Course Program (without outcomes listed)

NOTICE: The 2019 BBTC Program will apply for the ABSA International (American Biological Safety Association) Certification Maintenance Points (CM Pts) for biosafety professionals: General Session 2.0 CM Points; Animal Session 1.5 CM Points; Plant Session 1.5 CM Points.

Animal Biosafety and Biosecurity Session: July 8 – 9 (AM), 2019 – Animal Session Instructors


Monday July 8


8:00 AM – Noon:
Lab Animal Biosafety Level–2 (ABSL–2) and ABSL–3 Containment and Management
Lon Kendall, Director, Laboratory Animal Resources, Colorado State University, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above sessions, participants will be able to:
– list containment criteria necessary for Small Animal ABSL-2 and ABSL-3 facilities
– describe the difference between PPE for ABSL-2 and ABSL-3
– define mechanisms of decontamination of small animal ABSL-3 facilities
– list vaccines which may be available for added protection of individuals who have contact with the research animals
– define methods to prevent development of allergies in lab animal care personnel
– outline a training program for research personnel
– prepare for and respond to audits and inspections

Noon – 1:00 PM – Lunch

1:00 – 2:45 PM: Biosafety in Prion Disease Research
Candace Mathiason, Associate Professor, Microbiology, Immunology and Pathology Department; Colorado State University, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– describe how abnormal prions multiply within a host
– describe how prions are detected
– describe why normal prions do not cause disease
– describe how abnormal prions can be contaminated or destroyed in vitro

2:45 -3:00 PM – Break

3:00 – 5:00 PM: ABSL-2 Field Investigations
Bob Ellis, BBTC Director, Professor, Microbiology, Immunology and Pathology Department; and Colorado State University Director of Biosafety, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– understand how to conduct risk assessment and risk management for field research
– describe risks in the field which do not apply to laboratory research
– understand how to adapt personal protective equipment to field research


Tuesday Morning July 9


8:00 AM – Noon:
Large Animal Facilities and Containment, Animal Biosafety Level–2 (ABSL–2) and ABSL–3
Erin Smith, Biosafety Specialist at Kansas State University’s Biosecurity Research Institute (BRI), Kansas State University, Manhattan, Kansas, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– list several criteria necessary for Large Animal ABSL-3 facilities that differ from Small Animal facilities
– explain the difference between ABSL-3 and ABSL-3 AG (Agriculture)
– practice safe handling of large animals in ABSL-3 and ABSL-3 AG containment
– define mechanisms of decontamination of large animal ABSL-3 facilities
– respond to emergencies in BSL-3 and BSL-3 AG large animal containment
– describe the PPE necessary for different types of ABSL-3 research
– prepare for and respond to audits and inspections

Noon – 1:00 PM – Lunch



General Biosafety and Biosecurity Session: July 9 (PM) – 10 – 11 (AM), 2019 – General Session Instructors


Tuesday Afternoon July 9


1:00 – 1:30 PM:
Philosophy of Global BBTC; Ethics and Culture of Biosafety
Bob Ellis, BBTC Director, Professor, Microbiology, Immunology and Pathology Department; and Colorado State University Director of Biosafety, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– list mechanisms utilized to build a safe research environment
– describe how to apply the concepts of biosafety learned in the BBTC-Global
– define an integrated, comprehensive biosafety program

1:30 – 2:15 PM: The Importance of Safe Research Practices
Jim Welch, Affiliate, Elizabeth R. Griffin Program, Center for Global Health Science and Security, Georgetown University, Washington, D.C., USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– list how lapses in local biosafety affect global biosafety perceptions
– list how a comprehensive biosafety program benefits everyone in infectious disease research
– list mechanisms utilized to establish a bio-safe culture

2:15 -2:30 PM – Break

2:30 – 5:00 PM: BSL–2 and BSL–3 Building Design and Operations
Jerry Tews, Commissioning Biocontainment Specialist, Madison, Wisconsin, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– List required and recommended design criteria for BSL-2 and BSL-3 facilities
– Identify resources for design planning
– Identify potential pitfalls in BSL-2 and BSL-3 laboratory design
– List ongoing operational requirements for biocontainment facilities

6:00 – 9 PM – Dinner at Old Town Coopersmith’s Pool Parlor


Wednesday July 10 (Hawaiian Shirt Day)


8:00 – 10:30 AM :
Risk Assessment and Risk Management Application
Bob Ellis, BBTC Director, Professor, Microbiology, Immunology and Pathology Department; and Colorado State University Director of Biosafety, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– conduct a risk assessment
– list and utilize important criteria for biosafety management programs
– successfully develop risk management applicable to local biological risk situations
– develop a biosafety management program
– better communicate biological risk management to the public
– develop proactive rather than reactive risk management programs

10:30 – 10:45 AM – Break

10:45 AM – Noon: Design and Management of Insectaries
Nicholas Bergren, Arthropod-borne and Infectious Diseases Laboratory (AIDL); Microbiology, Immunology and Pathology Department, Colorado State University, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– list the basic criteria for designing insectaries
– list the most common reasons for unintentional release of insects from insectaries
– apply best management practices for insectaries
– apply insectary design criteria to optimize containment

Noon – 1:00 PM – Lunch

1:00 – 3:00 PM: Clinical and Public Health Lab Biosafety
Michael Pentella, Director of the State Hygienic Laboratory (SHL), University of Iowa College of Public Health, Iowa City, Iowa, USA

LEARNING OUTCOMES:
– Outline a Biosafety Program which addresses the safe containment and analysis of specimens submitted to a hospital clinical laboratory or a public health laboratory.
– Implement a program that would enable public health lab personnel to safely collect specimens in the field.
– Suggest mechanisms for handling specimens which would enhance the safety of the lab personnel and patients in a hospital environment.

3:00 -3:15 PM – Break

3:15 – 5:00 PM: The U. S. Select Agent Program; and Dual Use Research of Concern: Guidelines and Oversight
Bob Ellis, BBTC Director; Professor, Microbiology, Immunology and Pathology Department; and Colorado State University Director of Biosafety, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– define when registration is needed and how to register an entity
– state the basics of the Select Agent regulations
– understand the Select Agent Tier 1 regulations
– state when select agent program amendments are required
– describe how to request an amendment to an entity’s current registration
– understand the criteria for recognizing Dual Use Research of Concern (DURC)
– assist the research community in recognizing and mitigating DURC
– incorporate DURC in training programs



Thursday Morning July 11


8:00 – 10:00 AM:
Preparing for and Responding to Audits and Inspections
Joe Kozlovac, Agency Biosafety Officer, USDA–ARS, Beltsville, Maryland, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– prepare for audits and inspections
– host an audit or inspection
– know what should not be part of an inspection or audit
– properly report results of audits and inspections

10:00 -10:15 AM – Break

10:15 AM – Noon: Biosafety Cabinets (BSCs) Operation and Certification
Sara Cope, Assistant Biosafety Officer, Colorado State University, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– describe HEPA filter functions
– differentiate the classes of biosafety cabinets
– list criteria used to certify biosafety cabinets
– describe proper technique for decontamination of a biosafety cabinet
– understand why biosafety cabinets require annual certification

Noon – 1:00 PM – Lunch


Plant Biosafety and Biosecurity Session: July 11 (PM) – 12, 2019 – Plant Session Instructors


Thursday Afternoon July 11


1:00 – 2:00 PM:
Crop Security and Disease; Overview of the U.S.A. National Plant Diagnostic Network
Thaddeus Gourd, PhD, Colorado State University Extension Director and Agriculture Agent for Adams County, Colorado, Brighton, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– understand criteria for crop biosecurity
– understand and describe how the crop security network functions
– define the diseases that are the main focus of the crop diagnostic network
– understand and describe how a plant diagnostic lab functions

2:00 – 3:15 PM: Transgenic Plants in the Laboratory, the Greenhouse and in the Field
June Medford, Professor, Biology Department, Colorado State University, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– describe containment principles for transgenic plants
– understand and describe mechanisms for producing transgenic plants
– define criteria for field research with transgenic plants

3:15 -3:45 PM – Break

3:45 – 5:00 : Agricultural Biosecurity: Why it’s important. Steps to compliance
Emily Luna, Lab Manager, Bioagricultural Sciences and Pest Management Department, Colorado State University, Fort Collins, Colorado, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– understand and describe a select agent program for plant diseases
– describe containment principles for plants with infectious diseases
– prepare for and respond to audits and inspections


Friday July 12


8:00 – 10:00 AM:
Regulations and Permit Procedures for Plants, Plant Pests and Pathogens, Including Transgenics and Soils
Steven Ziegenfuss , Biological Safety Specialist, Iowa State University, Ames, Iowa, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– state when USDA (United States Department of Agriculture) permits are required for shipping of animal specimens
– state when USDA permits are required for shipping of plant materials
– state when USDA permits are required for shipping soil
– understand how to successfully register and apply for USDA permits
– contact the correct personnel when permit problems and questions arise
– prepare for and respond to audits and inspections

10:00 -10:15 AM – Break

10:15 AM – Noon, lunch Noon – 1:00 PM, 1:00 – 5 PM: Containment Greenhouse Design, Construction, and Management, and Containment Greenhouse Tour
Dann Adair, Controlled Environments, Inc., North Branch, Minnesota, USA

LEARNING OUTCOMES:
Upon completion of the above session, participants will be able to:
– find and use the guidelines for containment greenhouse design
– apply NIH plant biosafety levels to plant research
– describe the differences between plant containment levels Biosafety Safety Level-1 Plant (BL1-P) – BL4 – P
– understand and apply greenhouse management principles
– list and apply the four main elements of greenhouse containment
– understand basic construction principles for greenhouses